期刊论文

中文

世界科学技术-中医药现代化

1674-3849

2022

24

2

534-539

10.11842/wst.20210315013

国家自然科学基金委员会资助项目（81603634）：基于线粒体通透性转化研究知柏地黄丸提高解脲脲原体感染大鼠精子活力的机制，负责人：宾东华； 湖南省卫生健康委科研立项课题（20200745）：从AMPK/PPARα信号通路研究知柏地黄丸调控UU感染大鼠生精细胞能量代谢的效应机制，负责人：宾东华； 湖南中医药大学与湖南东健药业有限公司横向合作项目（50010138）：基于体质辨识的男性不育症代谢组学研究及龟鹿二仙膏的干预机制研究，负责人：周青；

本校为第一机构

肠道菌群的稳态、与人体阴阳平衡、脾肾功能密切相关，且与正常精子的发生有着密切关联。本文从肠道菌群稳态角度对龟鹿二仙胶治疗少弱精子症进行方药探析，认为龟鹿二仙胶通过调节人体肠道菌群稳态平衡阴阳，从而达到改善少弱精子症作用，为进一步研究龟鹿二仙胶对肠道菌群的影响以及与精液质量的关系提供理论依据。

The homeostasis of the intestinal flora is closely related to the balance of yin and yang of the human body, the spleen and kidney function, and the homeostasis of the intestinal flora is closely related to the occurrence of normal sperm. In this article, from the perspective of intestinal flora stable state, prescription drug analysis was carried out in the treatment of oligoasthenosis by Guilu Erxian Glum. It is believed that the Guilu Erxian Glum can improve the effect of oligoasthenosis by regulating the stable balance of yin and yang in the human intestinal flora homeostasis, which provid...