期刊论文

Jiang, S.S.

中文

南方医科大学学报

1673-4254

2010

30

11

2449-2451

10.12122/j.issn.1673-4254.2010.11.009

国家中医药管理局基金（2000-j-p-11）~~；

本校为第一机构

目的观察疏肝理脾方对慢性乙型肝炎Th1/Th2型细胞因子与肝功能及乙肝病毒复制的影响. 方法选择符合慢性肝炎诊断标准者86例, 随机分为治疗组(44例)和对照组(42例). 对照组采用西医护肝疗法, 治疗组在此基础上再服用疏肝理脾方剂. 分别观察治疗前后患者症状、体征、肝功能、HBV-DNA、HbeAg、IFN-γ、IL-2、IL-6、IL-10的变化情况. 结果治疗组疗效优于对照组, 两组总有效率分别为78.13%和57.14%(P

OBJECTIVE: To investigate the effect of Shuganlipi decoction on Th1/Th2 cytokines, liver function and HBV replication in patients with chronic hepatitis B (CHB). METHODS: Eighty-six confirmed CHB cases were randomly divided into control group (n=42) and experimental group (n=44) for treatment with routine western medication and additional treatment with Shuganlipi decoction, respectively. The production of IFN-gamma, IL-2, IL-6, IL-10 and liver function, HBV DNA, and HBeAg were detected in all the patients. RESULTS: The total response rate to the treatment was significantly higher in the exper...