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Potential application of traditional Chinese medicine in cerebral ischemia-Focusing on ferroptosis

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成果类型:
期刊论文
作者:
Zhao, Fengyan;Peng, Caiwang;Sun, Yang;Li, Hengli;Du, Ke;...
作者机构:
[Du, Ke; Peng, Caiwang; Sun, Yang; Li, Hengli; Zhao, Fengyan; Liu, Fang] Hunan Univ Chinese Med, Sch Pharm, Changsha, Peoples R China.
[Peng, Caiwang; Sun, Yang; Li, Hengli; Zhao, Fengyan; Liu, Fang] Ctr Standardizat & Funct Engn Tradit Chinese Med H, Changsha, Peoples R China.
[Peng, Caiwang; Sun, Yang; Li, Hengli; Zhao, Fengyan; Liu, Fang] Educ Dept Hunan Prov, Key Lab Modern Res TCM, Changsha, Peoples R China.
语种:
英文
关键词:
Traditional Chinese Medicine(TCM);cerebral ischemia;ferroptosis;Apoptosis;Autophagy
期刊:
Frontiers in Pharmacology
ISSN:
1663-9812
年:
2022
卷:
13
页码:
3280
基金类别:
National Natural Science Foundation of China [81704064]; Natural Science Foundation of Hunan Provincial [2022JJ30436]; Outstanding Youth Program of Scientific Research of Hunan Provincial Department of Education [20B434]; Natural Science Foundation of Changsha City [kq2202259]; Scientific Research Project of Hunan Provincial Administration of Traditional Chinese Medicine [202177]; Chinese medicine in Hunan Province [3]; 2021 Hunan University of Traditional Chinese Medicine Graduate Innovation Project [2021CX53]
机构署名:
本校为第一机构
院系归属:
药学院
摘要:
Traditional Chinese medicine (TCM) has attracted a great deal of attention in the treatment of cerebral ischemia is credited with the remarkable neuroprotective effects. However, the imperfect functional mechanism of TCM is a major obstacle to their application. Many studies have been conducted to illustrate the pathophysiology of post-ischemic cerebral ischemia by elucidating the neuronal cell death pathway. Meanwhile, a new type of cell death, ferroptosis, is gradually being recognized in various diseases and is becoming a new pathway of therapeutic intervention strategy to solve many health...

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