This research was funded by the National Natural Science Foundation of China (82304878 and 82204766), Natural Science Foundation of Hunan province (2022JJ40318 and 2023JJ40490), the Scientific Research Fund of Hunan University of Chinese Medicine (2021XJJJ006), and Xiaohe Sci-Tech Talents Special Funding under Hunan Provincial Sci-Tech Talents Sponsorship Program (2023TJ-X71), Scientific Research Project of Hunan Provincial Education Department (21B0394), Research Project of Hunan Administration of Traditional Chinese Medicine (B2023055), and Outstanding Youth Program of Hunan University of Chinese Medicine (202202).