期刊论文

中文

西北药学杂志

1004-2407

2011

26

4

241-243

10.3969/j.issn.1004-2407.2011.04.004

湖南省科技厅科研基金项目（编号:2009SK3121）；

本校为第一机构

目的 筛选产加兰他敏的内生真菌,为生产加兰他敏寻找新的途径.方法 以忽地笑鳞茎为实验材料,分离内生真菌,利用HPLC对其发酵代谢产物进行检测,筛选能产生加兰他敏的菌株.结果 从忽地笑鳞茎中分离出5株内生真菌,经HPLC分析,真菌GF-1能产生加兰他敏.经初步鉴定,GF-1为半知菌亚门(Deuteromycotina)青霉属(Penicillium LK.ex Fries).结论 忽地笑内生真菌有希望成为生产加兰他敏的新资源.

Objective To screen the producing galanthamine fungi from Lycoris aurea bulbs,and to explore a new way to produce galanthamine.Methods Endophyte was isolated from Lycoris aurea bulbs,and the fermentation solubles were screened and detected by HPLC.Results Five endophytic fungi were isolated from Lycoris aurea bulbs,in which the fungus named GF-1 proved to be able to produce galanthamine.By preliminary identification,GF-1 was a strain of Deuteromycotina,Penicillium LK.ex Fries.Conclusion Endophyti...