期刊论文

Determination of residual styrene monomer in 5-layer co-extrusion films used for infusion samples and in raw materials by GC

中文

西北药学杂志

1004-2407

2013

28

4

359-361

10.3969/j.issn.1004-2407.2013.04.012

本校为第一机构

目的 建立气相色谱法测定五层共挤膜输液用膜及原材料中残留单体苯乙烯的含量.方法 用二硫化碳溶剂提取样品,使用6 890 N气相色谱仪,色谱柱为DB-624石英毛细管柱（30 m×0.25 mm×1.20 μm）,进样口温度：200 ℃,氢火焰离子化检测器温度：300 ℃,采用程序升温,进样量：1 μL.结果 苯乙烯在0.05～2.0 μg·mL-1范围内线性关系良好（r=0.998 9）,最低检测限达1 mg·kg-1.结论 所建立的气相色谱法稳定性好、准确度高,可用于五层共挤膜输液用膜及原材料中残留单体苯乙烯的测定.苯乙烯在输液用膜及原材料中的残留量均符合GB 9692-1988食品包装用聚苯乙烯树脂卫生标准中小于0.5%的规定.

Objective To establish a gas chromatography method for the determination of residual styrene monomer in 5-layer co-ex- trusion films used for infusion samples and in raw materials. Methods Styrene was extracted by carbon disulfide,and then analyzed by 6 890 N gas chromatograph with a DB-624 quartz capillary column （30 m×0.25 mm×1.20 μm） by using temperature-pro- grammed. Temperatures of inlet and detector were 200 and 300 ℃ （FID）, respectively. Injection volume was 1 μL. Results Styrene had a good linear relationship in the range of 0....