Natural Science Foundation of Hunan Province [2020JJ4476]; Scientific Research Project of Hunan Provincial Education Department [19A379]; Scientific Research Project of Hunan Provincial Health and Family Planning Commission [20201617]; Hunan Province's domestic first-class construction discipline TCM discipline project [2022ZYX13]; Open Fund of First-class Discipline of Chinese Medicine of Hunan University of Chinese Medicine [2021ZYX40]; Quality Project of Postgraduate Training of Hunan University of Chinese Medicine [2021CX19]
机构署名:
本校为第一且通讯机构
院系归属:
第一中医临床学院
摘要:
ETHNOPHARMACOLOGICAL RELEVANCE: Yi Qi Huo Xue Fang (YQHXF) is an effective formula for treating cerebral ischemic stroke (CIS). However, its active ingredients and mechanism of action remain unclear. AIM OF THE STUDY: This study aimed to reveal the mechanism of action of YQHXF in the treatment of ischemic stroke based on network pharmacology and experimental validation. MATERIALS AND METHODS: This study identified the chemical components in YQHXF and the components absorbed by rat serum based on UPLC-Q-TOF/MS technology and used network pharmac...