期刊论文

Yue, Z.-H.

中文

世界华人消化杂志

1009-3079

2016

24

23

3508-3516

10.11569/wcjd.v24.i23.3508

:国家重点基础研究计划基金资助项目 :No.2014CB543102.the National Key Basic Research Development Program,No.2014CB543102

本校为第一且通讯机构

目的:通过固定循经取穴配伍以不同部位选穴进行对比研究,以糖尿病胃轻瘫（diabetic gastroparesis,DGP）大鼠为观察对象,研究不同按部选穴针刺治疗对DGP大鼠Rho A/ROCK信号的表达差异,探讨按部选穴是影响腧穴配伍效应的主要影响因素.方法:将60只♂SPF级SD大鼠,适应性喂养1 w k后,随机分为空白对照组、模型组、足三里+中脘组、足三里+内关组、足三里+非经非穴组,每组12只.除空白对照组12只外,其余48只大鼠运用链脲佐菌素腹腔注射造糖尿病模型,普通喂养8 wk后建立DGP大鼠模型,针刺治疗4 wk,于13 w k末墨汁灌胃后处死,取胃窦组织.运用Western blot检测胃窦平滑肌组织Ras同源物基因组成员A（Ras hom...

AIM: To observe the effect of acupuncture at different acupoints on the RhoA/ROCK signaling pathway in the gastric antrum of diabetic gastroparesis (DGP) rats. METHODS: Sixty SD rats were randomly divided into a normal group, a model group, a Zusanli + Zhongwan group, a Zusanli + Neiguan, and a Zusanli + non-acupoint group, with 12 rats in each group. DGP was indueced by intraperitoneal injection of streptozotocin, followed by feeding for 8 wk. After 4 wk of treatment, the gastrointestinal transit rate was measured with black ink. The expressio...