[Liao, Duan-Fang; Zheng, Xing] Hunan Univ Chinese Med, Div Stem Cell Regulat & Applicat, State Key Lab Chinese Med Powder & Med Innovat Hu, Changsha 410208, Hunan, Peoples R China.
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81273537]; Scientific Research Fund of Hunan Provincial Education DepartmentHunan Provincial Education Department [12K095]; Ministry of Education of the People's Republic of ChinaMinistry of Education, China [20809]
机构署名：
本校为其他机构
院系归属：
药学院
摘要：
A series of trifluoromethylated aurone derivatives were synthesized, and the structure of 6‐hydroxy‐4‐trifluoromethylated aurone was determined by single crystal X‐ray analysis. Their anticancer activities against leucocythemia (HL‐60) and colorectal adenocarcinoma (HT‐29) were evaluated by the standard MTT method in vitro with 5‐fluorouracil as a positive contrast drug. The results showed that all the (Z)‐trifluoromethylated aur...
