Clostridium difficile (CD), as one of the normal flora in human and animal intestine, is a Gram-positive anaerobic bacillus. It could cause opportunistic infections, resulting in CDassociated diarrhea, CD-associated colitis and other intestinal diseases. There have ever been massive epidemics of CD infection in both China and other countries, and it has became a global public health problem. The main pathogenic toxins of CD are toxin A, toxin B and newly discovered binary toxins (CDT). For CD infection prevention and treatment, the reasonable u...
