Synergistic anti-liver cancer effects of curcumin and total ginsenosides

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Deng, Zhe;Xu, Xiao-Yan;Yunita, Fenny;Zhou, Qing;Wu, Yong-Rong;...

通讯作者：

Tian, Xue-Fei

作者机构：

[Tian, Xue-Fei; Deng, Zhe; Yunita, Fenny] Hunan Univ Chinese Med, Coll Integrated Chinese & Western Med, Dept Internal Med, Changsha 410208, Hunan, Peoples R China.

[Tian, Xue-Fei; Xu, Xiao-Yan] Hunan Univ Chinese Med, Hunan Key Lab Translat Res Formulas & Zheng Tradi, Changsha 410208, Hunan, Peoples R China.

[Zhou, Qing] Hunan Univ Chinese Med, Affiliated Hosp 1, Changsha 410208, Hunan, Peoples R China.

[Wu, Yong-Rong; Hu, Yu-Xing] Hunan Univ Chinese Med, Sch Basic Chinese Med Sci, Changsha 410208, Hunan, Peoples R China.

[Wang, Zhi-Qi] Hunan Univ Chinese Med, Coll Pharmaceut Sci, Changsha 410208, Hunan, Peoples R China.

通讯机构：

[Tian, Xue-Fei] H

Hunan Univ Chinese Med, Coll Integrated Chinese & Western Med, 300 Xueshi Rd, Changsha 410208, Hunan, Peoples R China.

语种：

英文

关键词：

Total ginsenosides;Curcumin;Liver cancer;Immune;Inflammation;Programmed cell death 1 ligand 1

期刊：

世界胃肠肿瘤学杂志：英文版(电子版)

ISSN：

1948-5204

年：

2020

卷：

期：

页码：

1091-1103

DOI：

10.4251/wjgo.v12.i10.1091

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81473617]; Science and Technology Department of Hunan Province [2017SK50310]; Hunan Education Department's Science and Research Project [16K066]

机构署名：

本校为第一且通讯机构

院系归属：

第一中医临床学院

中西医结合学院

药学院

摘要：

BACKGROUND Liver cancer is the sixth most frequently occurring cancer in the world and the fourth most common cause of cancer mortality. The pathogenesis of liver cancer is closely associated with inflammation and immune response in the tumor microenvironment. New therapeutic agents for liver cancer, which can control inflammation and restore cellular immunity, are required. Curcumin (Cur) is a natural anti-inflammatory drug, and total ginsenosides (TG) are a commonly used immunoregulatory drug. Of note, both Cur and TG have been shown to exert anti-liver cancer effects. AIM To determine the s...

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Synergistic anti-liver cancer effects of curcumin and total ginsenosides

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