期刊论文

中文

湖南中医药大学学报

1674-070X

2012

32

9

25-28

10.3969/j.issn.1674-070X.2012.09.006.025.04

10C1043:湖南省教育厅项目 :湖南省高等学校科技创新团队建设项目

本校为第一机构

目的 观察护卵汤对GnRHa超排卵大鼠卵巢形态的影响,为护卵汤辅治ART提供相关理论依据.方法 模仿人类辅助生殖中的长周期,对大鼠进行GnRHa垂体降调节后再用HMG等药物超排卵(模型组),同时随机给予不同剂量的护卵汤辅助治疗(分别为护卵汤低、中、高剂量组),以自然周期未使用任何药物的大鼠为正常对照(正常组).在HCG日称体质量并计算各大鼠卵巢指数,光镜观察排卵前卵泡并计算优质卵泡率,电镜观察卵母细胞的超微结构.结果 护卵汤中剂量组的卵巢指数明显高于模型组,差异有统计学意义(P＜0.01)；模型组和护卵汤各剂量组的卵巢指数均高于正常组,差异有统计学意义(P＜0.05或＜0.01)；模型组的优质卵泡率明...

Objective To observe the effects of Huluantang on the ovarian morphology in rats under GnRHa controlled ovarian hyperstimulation（COH）, and to provide related basis for Huluantang in assisted reproductive technology （ART）. Methods Accroding to the human long period of COH, the modeling rats were established by pretreated with GnRHa for pituitary downregulation and then treated with HMG. Then, these rats were randomly divided into ART Huluan- tang high-dose group, median-dose group and low-dose group. At the same time, a number of rats withou...