期刊论文、会议论文

Establishment of rat model with chronic cough in yang deficiency of spleen and kidney

中文

湖南中医药大学学报

1674-070X

2010

30

9

358-361

全国第十一次中医诊断学术年会

全国第十一次中医诊断学术年会论文集

2010-07-01

中国北京

10.3969/j.issn.1674-070X.2010.09.009.030.04

湖南省自然科学基金(项目07JJ6042、07JJ4006);湖南中医药大学中医诊断国家重点学科联合资助

本校为第一机构

目的在慢性咳嗽模型制备的同时模拟脾肾阳虚模型,初步研究制造切实可行与临床证候相吻合的脾肾阳虚慢性咳嗽的动物模型。方法将SD雄鼠大鼠随机分为4组:正常对照组、慢性咳嗽组(慢咳组)、脾肾阳虚组、脾肾阳虚慢性咳嗽组(病证模型组),正常对照组无任何干预措施;慢咳组每日以香烟烟熏;脾肾阳虚组以番泻叶灌胃,并以冰水湿润皮毛后电风扇吹干。病证模型组:同时给予慢咳组和脾肾阳虚组两种处理方法,即先烟熏,再以番泻叶灌

Objective To investigate establishment of the rat model with chronic cough in yang deficiency of spleen and kidney based on chronic bronchitis model.Methods All the SD male rats were divided randomly into 4 groups,namely normal control（NC）,chronic bronchitis（CB）,yang deficiency of spleen and kidney（YDSK）,and YDSK with chronic bronchitis and（YDSKCB）.The rats in NC group were without any disposal,in CB stimulated by cigarette smoking,in YDSK gavaged with folium sennae solution and washed with ice water,then dried their furs with electric ...