Mechanism of Wuyao–Ginseng Medicine Pair in the Prevention and Treatment of Diarrhea-Type Irritable Bowel Syndrome Based on Gene Expression Omnibus Chip Data
Provincial Natural Science Foundation of Hunan [2022JJ70028, 2018JJ6040]; Scientific Research Fund of Hunan Provincial Education Department [19A372]; Key Project of TCM Research Plan of Hunan Province [2021016]
机构署名：
本校为第一机构
院系归属：
第一中医临床学院
摘要：
Abstract: Based on a Gene Expression Omnibus (GEO) chip analysis combined with network pharmacology and molecular docking technology, in this study we explored the molecular targets and mechanism of the wuyao–ginseng medicine pair in the prevention and treatment of diarrhea-type irritable bowel syndrome (IBS-D). The Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) was used to search for the chemical constituents and targets of wuyao and ginseng. The UniProt database was used to search for the target gene...
