期刊论文

Clinical efficacy of levocarnitine combined with alprostadil in the treatment of diabetic nephropathy and the influence on serum Cys C and retinol binding protein levels

中文

海南医学

1003-6350

2018

29

2

183-186

10.3969/j.issn.1003-6350.2018.02.011

本校为第一机构

目的 探讨左卡尼汀联合前列地尔治疗糖尿病肾病(DN)的疗效及其对患者血清半胱氨酸蛋白酶抑制剂C(Cys C)及视黄醇结合蛋白(RBP)水平的影响.方法 将2014年4月至2017年4月期间入住湖南中医药大学第一附属医院内分泌科的150例DN患者按照随机数表法分为对照组(n=74)与观察组(n=76),两组均根据患者发病情况首先给予基础治疗,对照组在此基础上联合前列地尔治疗,观察组在对照组基础上联合左卡尼汀治疗,疗程均为4周.比较两组患者的临床疗效及治疗前后的血清Cys C及RBP水平,采用SF-12生活质量量表评价两组患者治疗前后的生活质量.结果 (1)观察组患者的临床治疗总有效率为93.42%,明显高于对照组的70.27%,差...

Objective To investigate the clinical efficacy of levocarnitine combined with alprostadil in the treatment of diabetic nephropathy(DN)and its effect on serum cysteine inhibitor C(Cys C)and retinol binding protein(RBP)in patients.Methods A total of 150 patients with DN in the Department of Endocrinology,the First Hospital of Hunan University of Chinese Medicine from April 2014 to April 2017 were enrolled.The patients were divided into con-trol group(n=74)and observation group(n=76)according to random number method.Based on basic treatment,the co...