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Lower synaptic density associated with gaming disorder: an 18F-SynVesT-1 PET imaging study

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成果类型:
期刊论文
作者:
Jiale Hou;Qian Xiao;Ming Zhou;Ling Xiao;Ming Yuan;...
通讯作者:
Dong, H.;Hu, S.
作者机构:
[Jiale Hou; Ming Zhou; Ling Xiao; Shuo Hu] Department of Nuclear Medicine, Central South University, Changsha, Hunan, China
[Huixi Dong; Qian Xiao] Mental Health Center of Xiangya Hospital, Central South University, Changsha, Hunan, China
[Ming Yuan] Department of Applied Psychology, Hunan University of Chinese Medicine, Changsha, Hunan, China
[Na Zhong] Department of Substance Use and Addictive Behaviors Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
[Jiang Long] Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
通讯机构:
[Hu, S.] D
[Dong, H.] M
Mental Health Center of Xiangya Hospital, Hunan, China
Department of Nuclear Medicine, Hunan, China
语种:
英文
关键词:
Adolescent Behavior;Adolescent Psychiatry;Behavior, Addictive;Cognition
期刊:
综合精神医学
ISSN:
2096-5923
年:
2023
卷:
36
期:
5
页码:
e101112
基金类别:
This work was supported by the STI2030-Major Projects (grant number 2022ZD0211100; NZ), Foundation of Shanghai Mental Health Center (grant number 2021-YJ15; JL), National Natural Science Foundation of China (grant number 82272045; SH), National Natural Science Foundation of China (grant number 82201702; QX), Science and Technology Innovation Program of Hunan Province (grant number 2021RC4056; SH), Key Program of Ministry of Industry and Information Technology of China (grant number CEIEC-2022-ZM02-0219; SH), National Natural Science Foundation of China (grant number 82001405; HD), and Hunan Natural Science Foundation Youth Program (grant number 2021JJ40979; HD).
机构署名:
本校为其他机构
院系归属:
人文与管理学院
摘要:
Background Internet gaming disorder (IGD) is an ideal model to study the mechanisms underlying synaptic deficits in addiction as it eliminates the confounding effects of substance use. Synaptic loss and deficits are hypothesised to underlie the enduring maladaptive behaviours and impaired cognitive function that contribute to IGD. Aims This study aimed to determine whether subjects with IGD have lower synaptic density than control subjects and the relationship between synaptic density and IGD severity. Methods Eighteen unmedicated subjects diag...
摘要(中文):
Background Internet gaming disorder(IGD)is an ideal model to study the mechanisms underlying synaptic deficits...展开更多 Background Internet gaming disorder(IGD)is an ideal model to study the mechanisms underlying synaptic deficits in addiction as it eliminates the confounding effects of substance use.Synaptic loss and deficits are hypothesised to underlie the enduring maladaptive behaviours and impaired cognitive function that contribute to IGD.Aims This study aimed to determine whether subjects with IGD have lower synaptic density than contr...

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