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Network pharmacology approach to predicting the anti-cancer active ingredients of Ganfule,a Chinese Traditional Medicine Formula,against Hepatocellular carcinoma

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成果类型:
会议论文
作者:
Yu PAN;Shun-Xiang LI;Dan HUANG;Min-Qiu PAN
作者机构:
[Yu PAN; Shun-Xiang LI; Dan HUANG; Min-Qiu PAN] School of Pharmacy,Hunan University of Chinese Medicine
[Yu PAN; Shun-Xiang LI; Dan HUANG; Min-Qiu PAN] Hunan Hospitals of Traditional Chinese and Western Medicine
[Yu PAN; Shun-Xiang LI; Dan HUANG; Min-Qiu PAN] Liver Cancer Research Institute,Hunan Academy of Traditional Chinese Medicine
语种:
英文
关键词:
Ganfule formula;Chinese herbal medicine;hepatocellular carcinoma;network pharmacology;drug discovery and combination
年:
2013
页码:
233-250
会议名称:
2013年代谢组学与中医药现代研究学术论坛
会议论文集名称:
2013年代谢组学与中医药现代研究学术论坛论文集
会议时间:
2013-10-14
会议地点:
太原
会议赞助商:
科学技术部<&wdkj&>国际自然科学基金委<&wdkj&>中国药理学会
基金类别:
support form Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province(Grant No.2010/212);support from Hunan Provincial Innovation Foundation For Postgraduate(Grant No.2013)
机构署名:
本校为第一机构
院系归属:
药学院
摘要:
  Ethmopharmcology relevance: Ganfule(GFL),one of herbal medicines formula in china, has been widely used as the prevention of hepatic cirrhosis, hepatitical viral and liver cancer agent.However, its material basis that account for therapeutic effects and mechanisms of action at molecular-level remain unclear.Methods: Here, we constructed a computational systems approach that integrates druglikeness prescreening, ADME (absorption, distribution, metabolism, and excretion) prediction, molecular docking and multi-components, multi-targets, multi...
摘要(中文):
Ethmopharmcology relevance:Ganfule(GFL),one of herbal medicines formula in china,has been widely used as the prevention of hepatic cirrhosis,hepatitical viral and liver can...

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