scientific research project of traditional Chinese medicine of Hubei Provincial Health Commission [ZY2021M093]
机构署名：
本校为其他机构
院系归属：
第一中医临床学院
摘要：
Purpose: To screen the hypoglycemic active ingredients from Coptidis rhizoma, and study their targets as well as signal pathways via network pharmacology.Methods: The fifty-nine ingredients of Coptidis rhizoma were screened for. Their targets were confirmed by comparing with the hypoglycemic targets in DrugBank databases. The relationship between ingredients and targets was revealed through String database. The ingredient-targetpassageway network was constructed. Coptidis rhizoma was soaked in boiling water and concentrated. Rat models were rendered diabetic by the administration of streptozot...
