Objective:To observe the efficacy of Zhuhuang Granule No.2(ZHG2) in treating psoriasis vulgaris and on hemorheology.Methods:Eighty - three cases were divided randomly into two groups,the treated group with ZHG2 and the control group with composite indigo capsule,and the clinical effect and the scores of PASI were evaluated.Meanwhile,the change of hemorheology was measured.Results:The total effective rate in the treated group and the control group was 92.31% and 77.42% respectively with significant difference (P