期刊论文

中文

中华中医药学刊

1673-7717

2014

32

12

2983-2985

10.13193/j.issn.1673-7717.2014.12.055

国家自然科学基金项目（81473616） 湖南省科学技术厅科技计划重点项目（2013SK2025） 湖南省财政厅项目（2011湘财社指0036）

本校为第一机构

目的：试从干预高血压病炎症的角度,为复方钩藤降压片治疗高血压病及防治靶器官损害提供理论依据。方法：21只7周龄雄性自发性高血压大鼠（SHR）随机分为3组：模型组（SHR-S组）、复方钩藤降压片组（SHR-G组）、缬沙坦组（SHR-D组）,另7只WKY大鼠为空白对照组（WKY组）。无创测压仪测量血压,连续干预6周,ELISA法测定血清CRP、TNF-α、IL-6的水平。结果：1对血压的影响：自第1周开始,SHR-G组血压均低于SHR-S组（P〈0.01）,而均较SHR-D组、WKY组高（P〈0.01）,一直持续到实验结束;实验前后血压值比较：SHR-S组治疗前较治疗后升高（P〈0.01）,SHR-G组与SHR-D组治疗前较治疗后减低（P〈0.01）;2对炎...

Objective： From the intervention of inflammation to provide a theoretical basis for the Compound uncaria hypotensive tablet in the treatment and its effect of target organ damage in hypertension. Methods： 21 seven weeks old male SHR were randomly divided into 3 groups： SHR- S group,SHR- G group and SHR- D group and the other 7 WKY rats into normal control group. The blood pressure was determined by using instrument for measuring blood pressure in rats and the serum 1evels of CRP,TNF- αand IL- 6 were measured by ELISA after six weeks. Result...