Objective: To explore the curative of Electric -Acupuncture (EA)at Du meridian on the protective mecha- nism of cerebral ischemia injury. Methods : Fifty SD rats were randomly divided into normal group, model group, control group, Du meridian group,large intestine meridian group, 10 in each group. With permanent -thread plug method, set up the rat middle cerebral artery obstruction cerebral ischemia model (MCAO). According to the experimental scheme, the TYC staining method was used to detect cerebral infarction volume and immunohistochem...