期刊论文

中文

中华中医药学刊

1673-7717

2024

42

03

82-86+262-263

10.13193/j.issn.1673-7717.2024.03.015

82004283:国家自然科学基金 20201424:广东省中医药局面上项目 2021YF05:湖南中医药大学一方研究生创新项目

本校为第一机构

Objective To investigate the mechanism of Xinkang Granule(心康冲剂)regulating long non-coding RNA growth arrest specific transcript 5(LncGAS5)/DNA methyltransferase 3A(DNMT3A)pathway against myocardial fibrosis in rats with chronic heart failure.Methods Among 62 SD rats,6 rats were randomly selected as the normal group,and the remaining 56 rats were intraperitoneally injected with adriamycin to establish the chronic heart failure model.The 52 rats successfully modeled were randomly divided into the model group(12 rats,injected with PBS+normal s...