作者机构：
[李兰芳; 李峰; 杨莉; 毛小环; 柳威; 谢凤; 秦旭平; 郭玉; 陈临溪] Institute of Pharmacy and Pharmacology,University of South China;[李兰芳; 李峰; 杨莉; 毛小环; 柳威; 谢凤; 秦旭平; 郭玉; 陈临溪] Department of Physiology,Hunan College of Traditional Chinese Medicine;[李兰芳; 李峰; 杨莉; 毛小环; 柳威; 谢凤; 秦旭平; 郭玉; 陈临溪] Institute of Pharmacy and Pharmacology,University of South China,
会议名称：
中国活性氧生物学效应学术会议
会议时间：
2011-09-01
会议地点：
中国陕西西安
会议论文集名称：
中国活性氧生物学效应学术会议论文集（第一册）
摘要：
<正>Apelin is the endogenous ligand of the G protein coupled receptor,APJ.Vascular smooth muscle cells express both apelin and APJ,which are important regulatory factors in the cardiovascular systems. Previourly we reported that apelin-13 significantly stimulated vascular smooth muscle cell proliferation. However,little is known about the precise cellular mechanisms responsible for vascular smooth muscle cell proliferation induced by apelin-13.Here,we present novel data that indicate the key role of NADPH oxidase-derived reactive oxygen species in vascular smooth muscle cell proliferation treated by apelin-13. Apelin-13 stimulated reactive oxygen species production in a concentration and time-dependent manner. And DPI,a NADPH oxidase inhibitor,impaired apelin-13-induced reactive oxygen species generation and vascular smooth muscle cells proliferation.Apelin-13-treatment increased the expression of NADPH oxidase 4 in a dose-dependent manner.Down-regulation of NADPH oxidase 4 using siRNA prevented apelin-13-induced reactive oxygen species generation and vascular smooth muscle cells proliferation.An increase in reactive molecules can trigger the activation of ERKl/2 stress-sensitive signaling pathways but not P38 and JNK.In conclusion,Apelin-13 induced the vascular smooth muscle cells proliferation by NOX4-derived ROS via ERK1/2 signal pathway.
作者机构：
[Li, Qqiupin; Liu, Yi] Hunan Tradit Chinese Med Coll, Publ Lesson Dept, Zhuzhou 412012, Peoples R China.;[Gu, Lei] Hunan Univ Chinese Med, Dept Sports & Art, Changsha 410208, Hunan, Peoples R China.
会议名称：
8th International Symposium on Computer Science in Sport (IACSS 2011)
会议时间：
SEP 21-24, 2011
会议地点：
Shanghai, PEOPLES R CHINA
会议主办单位：
[Liu, Yi;Li, Qqiupin] Hunan Tradit Chinese Med Coll, Publ Lesson Dept, Zhuzhou 412012, Peoples R China.^[Gu, Lei] Hunan Univ Chinese Med, Dept Sports & Art, Changsha 410208, Hunan, Peoples R China.
关键词：
16th;Men;Basketball;Championship;Technique index
摘要：
Summing up the 11 technical indicators of 2010 FIBA World men's Championship top 16 teams, we analyzed and tested the data by using the factor analysis, Q-type clustering, rank correlation analysis methods. The results showed that: there are 6 technical indicators inflecting the teams' scores: defensive rebounds, block free throw percentage assist, three-point shot percentage and offensive rebounds. By using the factor analysis and Q-type analysis, we evaluated the technique and tactics index of basketball games. And the result is high reliability, which can objectively reflect the team's technical and tactical skill. This paper reveals technique and tactics development trends of the 2010 World Men's Basketball Championship top 16 teams, at the same time, a proper and efficient method to make quantitative evaluation of basketball teams' technique and tactics quality was explored.
作者机构：
Department of Sports Art of Hunan University of Chinese Medicine,Hunan Changsha,410208;湖南中医药大学体育艺术部 湖南长沙412012;Physical Education Staff Room of General Course Department of Hunan Traditional Chinese Medicine Col;湖南中医药高等专科学校公共课部体育教研室 湖南株洲412012
