In recent years, the incidence of thrombotic diseases is increasing, which is seriously harmful to human health. Existing clinical applications of anticoagulants can cause severe bleeding complications. Recent studies indicate that FⅪ-deifcient mice were fully protected from occlusive thrombus without severely prolonged bleeding times. hTe study of antithrombotic therapy by inhibiting of FⅪ has made remarkable progress. On the basis of FⅪ, a new target for antithrombotic drug, this paper reviews the effect of FⅪ on thrombus formation and th...
