Objective: To explore the effect of Qingning Zhike granules on pathological changes and ultrastructure of lung in model rats with cough variant asthma (CVA). Methods: Ovalbumin and capsalcin were used to duplicate the model rats of CVA. Rats were randomly divided into control group, model control group, prednisone acetate tablets group, Qingning Zbike granules group and TCM combined with hormone group. After 13 days of intragastric administration, rats were sacrificed. Results: Compared with the control group, the cough frequency increased...