Linalool, derived from Cinnamomum camphora (L.) Presl leaf extracts, possesses molluscicidal activity against Oncomelania hupensis and inhibits infection of Schistosoma japonicum

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成果类型：

期刊论文

作者：

Yang, Fan;Long, Erping;Wen, Juhua（文菊华）;Cao, Lei;Zhu, Chengcheng;...

通讯作者：

Wu, ZD

作者机构：

[Wen, Juhua; Ruan, Ying; Wang, Xiaoying; Wu, Zhongdao; Zhang, Limei; Zheng, Huanqin; Ji, Pengyu; Zhu, Chengcheng; Yang, Fan; Cao, Lei; Hu, Huanxin; Hu, Huiling; Wei, Xiaoxia; Wang, Chaofan; Long, Erping; Yang, Xiangyun; Lv, Zhiyue] Sun Yat Sen Univ, Zhongshan Sch Med, Guangzhou 510080, Guangdong, Peoples R China.

[Wang, Xiaoying; Wu, Zhongdao; Zhang, Limei; Zheng, Huanqin; Ji, Pengyu; Yang, Fan; Cao, Lei; Hu, Huanxin; Hu, Huiling; Wei, Xiaoxia; Wang, Chaofan; Long, Erping; Yang, Xiangyun; Lv, Zhiyue] Sun Yat Sen Univ, Key Lab Trop Dis Control, Minist Educ, Guangzhou 510080, Guangdong, Peoples R China.

[Wen, Juhua] Hunan Univ Chinese Med, Dept Physiol, Changsha 410208, Hunan, Peoples R China.

[Okanurak, Kamolnetr] Mahidol Univ, Fac Trop Med, Dept Social & Environm Med, Bangkok 10400, Thailand.

[Wu, Zhongdao] Sun Yat Sen Univ, Zhongshan Sch Med, 74 2nd Zhongshan Rd, Guangzhou 510080, Guangdong, Peoples R China.

通讯机构：

[Wu, ZD ] S

Sun Yat Sen Univ, Zhongshan Sch Med, 74 2nd Zhongshan Rd, Guangzhou 510080, Guangdong, Peoples R China.

语种：

英文

关键词：

Linalool;Oncomelania hupensis;Schistosoma japonicum;Molluscicidal activity;Schistosomicidal property;Cinnamomum camphora

期刊：

Parasites & Vectors

ISSN：

1756-3305

年：

2014

卷：

期：

页码：

1-13

DOI：

10.1186/1756-3305-7-407

基金类别：

We are grateful to Pro. Wang Shi Ping and Mr. Zhang Zhi Hai for their kind donation of O. hupensis. This work was supported by a grant from the National Basic Research Program of China (grant no. 2010CB530004), the National Natural Science Foundation of China (grant no. 30771888, 81371836 and 30800966), the 111 Project (grant no. B12003) and Research Fund for Students of Sun Yat-sen University (2011, 2013).

机构署名：

本校为其他机构

院系归属：

医学院

摘要：

Schistosomiasis japonicum remains a considerable economic and public health concern in China, the Philippines and Indonesia. Currently available measures to control the unique intermediate host Oncomelania hupensis are frequently associated with severe side effects. Previous studies have demonstrated that linalool-rich extracts from various plants exhibited promising biological activities including cytotoxic, anti-microbial and anti-parasitic properties. We identified the components of leaf extracts from Cinnamomum camphora by gas chromatograph...

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Linalool, derived from Cinnamomum camphora (L.) Presl leaf extracts, possesses molluscicidal activity against Oncomelania hupensis and inhibits infection of Schistosoma japonicum

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