期刊论文

Effects of huoxuelishui method on EGFmRNA expression on ERM of traumatic proliferative vitreoretinopathy in rabbits

Peng, Q.-H.

中文

国际眼科杂志：英文版

2222-3959

2012

12

1

25-29

10.3969/j.issn.1672-5123.2012.01.08

中国湖南省科技厅科研基金资助项目（No.02SSY3096） 中国湖南省自然科学基金资助项目（No.02JJY2035）

本校为第一且通讯机构

目的:探讨活血利水之散血明目片对外伤性增生性玻璃体视网膜病变（traumatic proliferrative vitreoretinopathy,tPVR）增殖膜（epiretinal membrane,ERM）中EGFmRNA表达的影响及防治PVR的作用机制。方法:将40只成年有色家兔随机抽取32只,制作tPVR模型,随机分成模型组（B组）、活血利水组（C组）、活血化瘀（D组）、利水明目组（E组）,另8只为空白组（A组）。连续灌胃30d后,观察眼底PVR分级情况,原位杂交法检测EGFmRNA在各组的表达,HE染色观察病理组织学改变。结果:给药7d后,B,D,E组PVR分级比较,差异无统计学意义（P>0.05）,给药30d后,C组与各组比较,差异有统计学意义（P

AIM: To study the effects of huoxuelishui method (HXLSM) on EGFmRNA's expression on epiretinal membrane (ERM) of traumatic proliferative vitreoretinopathy (tPVR) and its mechanism of curative and preventive effects on PVR. METHODS: Thirty-two rabbits were selected randomly from 40 healthy adult colored rabbits and induced to tPVR models, then divided into four groups: the first group was treated with sanxuemingmu tablet-huoxuelishui (HXLS) group, the second treated with zhixuequyu tablet-huoxuehuayu (HXHY) group, the third treated with zhulingsan-lishuimingmu (LSMM) group and the model group. ...