期刊论文

Meta Analysis of Replenishing Qi and Activating Blood prescription for Treatment of Vascular Dementia

中文

中国中医药现代远程教育

1672-2779

2018

16

8

47-51

10.3969/j.issn.1672-2779.2018.08.021

No.81603604:国家自然科学基金 No.2017SK2111:湖南省重点研发计划项目 No.2016JJ4064:湖南省自然科学基金 No.201594:湖南省中医药科研项目 201785:湖南省中医药科研项目 :湖南中医药大学大学生研究性学习和创新性实验计划

本校为第一机构

目的 评价益气活血方药治疗血管性痴呆的疗效和安全性.方法 利用计算机检索中国生物医学文献数据库、中国知网、万方数据库与维普数据库,检索时间均从建库至2017年6月,查找研究方案为随机对照实验(RCT),干预措施为益气活血方药治疗血管性痴呆且已发表的较高质量文献.采用RavMan 5.3.5软件进行Meta分析.结果 最终纳入的RCT 21篇,共1716例血管性痴呆患者.结果显示:益气活血方药联合西药治疗血管性痴呆总体临床疗效与单纯西药治疗比较,其差异有统计学意义[OR=2.69,95％CI(2.15,3.37),P＜0.00001];益气活血方药联合西药治疗血管性痴呆的MMSE评分与单纯西药治疗比较,差异有统计学意义[MD=2.68,95％CI...

Objective To evaluate the efficacy and safety of clinical research studies of replenishing qi and activating blood prescription in the treatment of vascular dementia. Methods CBM, CNKI, VIP and Wanfang database were electronically searched for randomized controlled trials（ RCTs） on replenishing qi and activating blood prescription in the treatment of vascular dementia（ from June 1994 to June 2017）. Two reviewers independently screened literature according to the inclusion and exclusion criteria,and meta-analyses were performed by using Rev ...