Objective:To observe the relationship between cortisol content in salivawith and syndrome differentiations.Method:91 patients were divided into four groups,19 cases of Deficient Cold(DC)group,20 cases of Deficient Heat(DH) group, 27 cases of Excess Heat(EH)group,25 cases of Intermingled Deficient and Excess (DH)group.The cortisol content in saliva were detected with radioimmunoassay.Result:The relations of the cortisol content among different syndrome differentiations were as below:DC group