期刊论文

Analysis on medication rules for treatment of dementia by ancient physicians based on data mining methods

Ge, J.-W.

中文

中国中药杂志

1001-5302

2018

43

16

3376-3381

10.19540/j.cnki.cjcmm.20180419.004

国家自然科学基金项目（81603604）； 湖南省重点研发计划项目（2017SK2111）； 湖南省自然科学基金项目（2016JJ4064）； 湖南省中医药科研项目（201594）； 湖南省教育厅科研项目（12C0268）；

本校为第一且通讯机构

基于历代医家治疗痴呆相关病症医案方药,探讨古代痴呆用药与组方规律。计算机加手工检索《中华医典》《中华传世医书》等中医文献集及数字图书馆记载的历代痴呆相关病症临证医案(囊括汉代至清代方书),建立历代医家治疗痴呆方药规范化数据库,运用频数统计与关联规则(Apriori算法、改进的互信息法与复杂系统熵聚类)分析方法挖掘历代医家治疗痴呆方剂的用药特点与组方规律。对最终筛选出的156首方剂、共123味中药进行分析,药物总频次11 747次,挖掘出8个核心方药。确定方剂中药物的使用频次和药物之间的规则与算法,发现历代医家治疗痴呆方剂的高频药物为茯苓、远志、人参、石菖蒲、甘草、当归、麦冬...

To analyze the medication features and regularity of prescriptions of Chinese medicine in treating patients with dementia based on ancient medical records. In the article, we retrieved the ancient medical records related to the treatment of dementia (from the Han Dynasty to the late Qing period) in Chinese Medical Classics, Chinese Ancient Medical Books and digital library, and then set up a medical records normalized database. The medication features and prescription rules for dementia were analyzed by frequency statistics and association rule...