期刊论文

中文

中南药学

1672-2981

2016

14

3

329-332

10.7539/j.issn.1672-2981.2016.03.028

本校为第一机构

目的 观察散血明目片联合雷珠单抗眼内注射治疗湿性年龄相关性黄斑变性(AMD)的疗效.方法 将77例(77眼)湿性AMD患者,采用随机原则分为联合治疗组(39眼)和雷珠单抗组(38眼).联合治疗组:散血明目片口服十雷珠单抗眼内注射;雷珠单抗组:雷珠单抗眼内注射.眼内注射每月1次,连续3次;散血明目片连续口服3月.通过最佳矫正视力,光学相干断层扫描(OCT)及眼底荧光血管造影(FFA)检查,分析治疗前后最佳矫正视力、黄斑视网膜厚度及视网膜渗漏的变化.结果 治疗后3个月最佳矫正视力联合治疗组(0.09±0.05 vs 0.38±0.14)、雷珠单抗组(0.08±0.04 vs 0.29±0.15)均有提高,治疗前后差异及治疗后组间差异均有统计学意...

Objective To evaluate the clinical curative effect of Sanxue Mingmu tablets combined with intravitreal injection of lucentis for the treatment of wet age-related macular degeneration （AMD）. Methods Totally 77 pa- tients （77 eyes） with wet AMD were randomly divided into 2 groups： a combined treatment group （39 eyes） and a lucentis group （38 eyes）. The combined treatment group was treated with Sanxue Mingmu tablets combined with intravitreal injection of lucentis. The lucentis group was treated with intravitreal injection of lucentis alo...