Objective:To observe the influence of yangxintongmai tablet to IRS rats ,hemorheology and insulin sensitivity and its action mechanism.Methods:To IRS rats yangxintongmai tablet therapeutic group, metformin hydrochloride tablet therapeutic group and pathology model group and health control group, We detected indexes of whole blood viscosity, plasma viscosity, hematocrit, blood platelet adhere rate and insulin sensitivity index and did relational analysis.Results:By comparing with the health control group, the indexes of hemorheology and insulin sensitivity are seriously abnormal in pathology mo...