版权说明 操作指南
首页 > 成果 > 详情

Effects of buddleja officinalis total flavonoids on serum testosterone level of castrated male rats with xeroma

认领
导出
下载 Link by 中国知网学术期刊 Link by 万方学术期刊
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
李海中;彭清华(彭清华);王芬;姚小磊;李文娟
通讯作者:
Peng, Q.-H.
作者机构:
[彭清华; 李文娟] Department of Ophthalmology, The First Hospital of Hunan University of Chinese Medicine, Changsha 410007, Hunan Province, China
Department of Ophthalmology, Loudi Central Hospital, Loudi 417000, Hunan Province, China
Department of Ophthalmology, Ningxiang Hospital of Traditional Chinese Medicine, Ningxiang County 410600, Hunan Province, China
Department of Ophthalmology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, Guangxi Zhuang Autonomous Region, China
[姚小磊] Department of Ophthalmology, The First Hospital of Hunan University of Chinese Medicine, Changsha 410007, Hunan Province, China, Department of Ophthalmology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, Guangxi Zhuang Autonomous Region, China
通讯机构:
[Peng, Q.-H.] D
Department of Ophthalmology, The First Hospital of Hunan University of Chinese Medicine, China
语种:
中文
关键词:
去势;干眼病;血清睾酮;密蒙花总黄酮
关键词(英文):
Buddleja officinalis total flavonoids;Castration;Testosterone;Xeroma
期刊:
国际眼科杂志
ISSN:
1672-5123
年:
2013
卷:
13
期:
11
页码:
2174-2178
基金类别:
国家自然科学基金面上资助项目(No.30772824) 教育部高等学校博士学科点专项科研基金资助项目(No.200805410004) 湖南省自然科学基金资助项目(No.07JJ3049) 湖南省科技厅科研基金资助项目(No.2009FJ3001) 湖南省研究生创新基金资助项目(湘财教字[2008]68号) 国家中医药管理局中医眼科学重点学科建设项目 湖南省中医五官科学重点学科建设项目
机构署名:
本校为第一且通讯机构
院系归属:
第一中医临床学院
摘要:
目的:观察密蒙花总黄酮对去势雄鼠干眼病大鼠模型基础泪液分泌量、泪膜稳定性及血清睾酮水平的影响,探讨密蒙花总黄酮抗性激素水平失调导致的大鼠干眼病的作用机制。方法:将1月龄健康雄性Wistar大鼠150只,体质量200 g左右,采用随机数字法分为5组,每组30只。分别为:A:正常组;B:假手术组;C:手术对照组;D:雄激素治疗组;E代表:密蒙花总黄酮治疗组;将C, D, E三组实验鼠切除双侧睾丸及附睾;B组只切开阴囊而不切除睾丸,作为假手术组;A组不做任何处理。各组在造模后1 wk ,待伤口基本愈合后开始用药。各组实验动物分别于用药1,3,5mo后随机取10只,行Schirmer Ⅰ试验( SⅠt)、...
摘要(英文):
AIM: To observe buddleja officinalis total flavonoids' effect on the basal tear secretion amount, tear film stability, lacrimal gland histomorphology and serum testosterone level of castrated male rat model with xeroma, to study the mechanism of rat xeroma caused by buddleja officinalis total flavones' anti-sex hormones disorders. MEATHODS: A total of 150 Wistar male rats of 1 month old, weighted about 200g, were randomly divided into 5 groups with 30 rats in each group with A representing normal group; B representing sham operation group; C representing surgery control group; D representing g...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com