期刊论文

中文

中医药导报

1672-951X

2006

12

3

1-4

10.13862/j.cnki.cn43-1446/r.2006.03.001

本校为第一机构

目的:比较慢性乙型重型肝炎阳黄证和阴黄证患者的树突状细胞功能。方法:体外培养上述病人外周血树突状细胞,流式细胞仪检测其表面分子CD80、CD86、CD40、HLA-DR、CD1a的表达,MLR中刺激T细胞的增殖和分泌IL-12、IFNα的能力。结果:阴黄证患者的DC表面分子CD86的表达较阳黄证组下降（P

Objective ：To compare the phenotypy and function of dendritic cells（DCs） in patients with two sub - type of TCM of chronic severe hepatitis Bo Method： 10 patients with chronic severe hepatitis were divided into 2 groups according to the charactefite of their icterus based on TCM （ Yang - icterus group and Ying - icterus group）, peripheral blood monocytes （PBMCs） were isolated from those patients. DCs were generated by culturing PBMCs in 1000 u/ml granulocyte - macrophage stimulating factor（ GM - CSF） and 500 u/ml IL -4 with serum -fre...