期刊论文

中文

神经解剖学杂志

1000-7547

2007

23

6

587-590

10.3969/j.issn.1000-7547.2007.06.004

2003CB515301:国家重点基础研究发展计划（973计划） 05JJ30028:湖南省自然科学基金

本校为其他机构

为探讨补阳还五汤对脊髓损伤后轴突再生及功能修复的影响，将SD大鼠C_3-C_4右侧红核脊髓束（RST）横断后，分别以补阳还五汤和蒸馏水连续灌胃8周，用BDA顺行束路示踪方法检测轴突再生情况，采用自发性直立探究行为学测试方法评判前肢运动功能的恢复。结果显示：灌服补阳还五汤组的大鼠在损伤RST的尾侧可见少量的BDA标记纤维，伤侧前肢使用率明显高于蒸馏水组（P〈0．01）。上述结果提示，补阳还五汤能促进大鼠横断的红核脊髓束轴突再生及部分功能修复。

To observe the effect of Buyang Huanwu Decoction （BYHWD） on axon regeneration and functional recovery of the animal after spinal cord injury （ SCI）, SD rats were given BYHWD or distilled water via gastrogavage after right rubrospinal tract （RST） transection at the level between C3 and C4. Eight weeks after treatment, the axon regeneration was examined by BDA anterograde tracing technique, and functional recovery was studied by a test of forelimb usage during spontaneous vertical exploration. The results showed that there were a few BDA la...