期刊论文

Kuang, Lin（匡琳）

英文

EXPERIMENTAL AND THERAPEUTIC MEDICINE

1792-0981

2017

14

3

2577-2583

10.3892/etm.2017.4815

The present study was supported by Chinese Nature Science Foundation (grant nos. 81202705 and 81373641) and by the Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases, and the Key Laboratory of Colleges and Universities in Hunan Province for Cytobiology and Molecular Biotechnology.

本校为第一且通讯机构

MicroRNAs (miRNAs) are 22-nucleotide single-stranded RNAs which regulate gene expression by targeting 3' untranslated regions. Previous studies have suggested that miRNAs may be used as markers for investigating the molecular regulation of gene expression. In the present study, miRNA and mRNA expression profiles were investigated using a massively parallel next generation sequencing technique to compare herpes simplex virus (HSV)2-infected (n=3) and healthy (n=3) epithelial tissues from guinea pigs. Total RNA was isolated and RNA sequencing was...