期刊论文

Yuan, Z.K.

中文

中国中西医结合杂志

1003-5370

2006

26

5

407-410

10.3321/j.issn:1003-5370.2006.05.005

国家自然科学基金项目（No.30271574）；

本校为第一机构

目的探讨血管内皮细胞功能在冠心痛（coronary heart disease,CHD）心血瘀阻证中的作用.方法对冠心病心血瘀阻证组112例、冠心病非心血瘀阻证组108例、非冠心病心血瘀阻证组110例和健康人对照组100名检测分析血管内皮细胞产生的一氧化氮（NO）、内皮素（ET）、血管紧张素Ⅱ（AgⅡ）、可溶性细胞间黏附分子（sICAM-1）和可溶性血管细胞黏附分子（sVCAM-1）等血管活性物质.结果ET、AgⅡ、sICAM-1和sVCAM-1的异常程度均呈CHD心血瘀阻证组＞CHD非血瘀证组＞健康人对照组的趋势（P＜0.05或P＜0.01）;而CHD心血瘀阻证组和非冠心病心血瘀阻证组之间差异无显著性（P＞0.05）.结论血管内皮细胞分泌的ET、...

OBJECTIVE: To explore the function of vascular endothelial cell (VEC) in patients with coronary heart disease (CHD) of Xin-blood-stasis syndrome. METHODS: Some vasoactive substances produced by VEC were detected and analyzed in patients with CHD of or without Xin blood stasis syndrome in group A (n=112) and group B (n=108) respectively, also in patients with non-CHD but of Xin-blood-stasis syndrome in group C (n=110), and healthy persons in group D (n=100), including nitric oxide (NO), endothelin (ET), angiotensin H (Ag II), soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascu...