期刊论文

中文

中国中医基础医学杂志

1006-3250

2002

8

8

20-21

10.3969/j.issn.1006-3250.2002.08.010

湖南省自然科学基金

本校为第一机构

为了研究牛角地黄冲剂对大鼠免疫性血小板减少模型T细胞亚群的影响,将100只SD大鼠随机分成空白对照组、模型对照组、强的松对照组、牛角地黄冲剂高剂量组和牛角地黄冲剂低剂量组.除空白组外,其余4组均注射兔抗大鼠血小板血清(APS)造模,分别灌药和蒸馏水,每日1次,连续11d,第11天测T细胞亚群,并做骨髓涂片检查.结果:牛角地黄冲剂高、低剂量组和强的松对照组CD4、CD8、CD4/CD8均显著高于模型组,以中药高剂量组作用明显,优于强的松组和低剂量组,说明中药牛黄地黄冲剂具有改善ITP大鼠细胞免疫功能低下的作用.

Objective:To study the effects of infusion niujiao Dihuang(NJDH)on rats Immunologic thrombocytopenic prupura(ITP) rats model were created by injected anti rat platelet serum(APS).Method:All rats were determined T cell subsets by ELISA methods and marrow by smear after 11 days.Result:The level of CD4、CD8、CD4/CD8 in the traditional Chinese medicine group and prednison group were significantly higher compared with that of model group( P