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Protective effects of Buyang Huanwu Decoction on axotomized rubrospinal neurons after spinal cord injury in rats

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成果类型:
会议论文
作者:
AN CHEN(陈安);Hui WANG;Xiao-Qion WU;Yong-mei SHI(石咏梅);Xue-Gang LUO;...
作者机构:
Department of Anatomy, Traditional Chinese Medicine University of Hunan, Changsha 410007, China
Department of Neurobiology, Central South University, Changsha 410013, China
Institute of Neurosciences, The Fourth Military Medical University, Xi'an 710032, China
语种:
英文
关键词:
Buyang Huanwu Decoction;axotomized neuron;cAMP;BDNF;TrkB
年:
2007
会议名称:
中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 5th Congress of the Chinese Society for Neuroscience)
会议论文集名称:
中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 5th Congress of the Chinese Society for Neuroscience)论文集
会议时间:
2007-10-24
会议地点:
杭州
会议主办单位:
中国神经科学学会
机构署名:
本校为第一机构
摘要:
  Objective To observe the effect ofBuyang Huanwu Decoction (BYHWD) on neuron protection.Methods SD rats were given BYHWD or distilled water via gastrogavage after right rubrospinal tract(RST) transection at the level between C3 and C4,8 week after treatment,rubrospinal neurons(RNs) were counted and mean cell size was examined by Nissl staining; concentration of cAMP in red nucleus was determined by radioimmunoassay; changes of BDNF and TrkB expression in RN was examed using immunohistochemistry.Results The number and mean cell size of RN was...

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