期刊论文

Effect of Method of Activating Blood and Diuresis on Expressions of Retinal VEGF and bFGF after Retinal Vein Occlusion

中文

中华中医药学刊

1673-7717

2010

28

5

908-910

10.13193/j.archtcm.2010.05.14.pengqh.025

湖南省科技厅科研基金资助项目（02SSY3096） 湖南省自然科学基金资助项目（02JJY2035）

本校为第一机构

目的:探讨活血通脉利水明目之散血明目片对视网膜静脉阻塞(Retinal vein occlusion,RVO)的治疗作用及防治并发新生血管的作用机理.方法:将48只家兔(96只眼)随机分为4组,每组12只(24只眼).分别为:A组:健康空白组;B组:模型组;C组:血栓通组;D组:散血明目片组.采用激光光凝法建立兔RVO模型,分别于术后第3、7、14、21天用空气栓塞法处死动物,即刺摘取眼球,取材、脱水、石蜡包埋切片.免疫组化法观察兔视网膜组织中血管内皮生长因子(VEGF)、碱性成纤维细胞生长因子(bFGF)的表达.结果:B、C、D3组72只眼成功建立了RVO模型.D组与B组比较,视网膜组织中VEGF、bFGF含量明显减少,差异有统计学意义(P0.05).结论...

Objective：To investigate the effects of SanXue MingMu Tablet（SXMMT） that can activating blood,Method：relieving meridians,eliminating dampness and dissipating stagnation on treatment of retinal vein occlusion（RVO） and the action mechanism of preventing the new blood vessel.Method：48 rabbits （96 eyes） were randomly divided into 4 groups,with 12 （24 eyes） in each one.Group A was normal group,group B was modeling group,group C was Xue Shuang Tong group and D was SXMMT group.RVO models were made by laser photocoagulation.Rabbits were kill...