Inhibition of Aortic Intimal Hyperplasia and Vascular Smooth Muscle Proliferation and Extracellular Matrix Protein Expressions by Astragalus-Angelica Combination

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成果类型：

期刊论文

作者：

Yan, Huifang;Peng, Xiwei;Xu, Hao;Zhu, Jiahuan;Deng, Changqing（邓常清）

通讯作者：

Deng, CQ

作者机构：

[Peng, Xiwei; Xu, Hao; Yan, Huifang; Zhu, Jiahuan] Hunan Univ Chinese Med, Mol Pathol Lab, Hunan Prov Key Lab Prevent & Treatment Integrated, Changsha 410208, Hunan, Peoples R China.

[Deng, Changqing] Hunan Univ Chinese Med, Mol Pathol Lab, Changsha 410208, Hunan, Peoples R China.

通讯机构：

[Deng, CQ ] H

Hunan Univ Chinese Med, Mol Pathol Lab, Changsha 410208, Hunan, Peoples R China.

语种：

英文

期刊：

Evidence-Based Complementary and Alternative Medicine

ISSN：

1741-427X

年：

2018

卷：

2018

页码：

1508637

DOI：

10.1155/2018/1508637

基金类别：

This study was supported by National Natural Science Foundation of China (no. 81473581).

机构署名：

本校为第一且通讯机构

院系归属：

医学院

中西医结合学院

摘要：

VSMC proliferation and ECM deposition always resulted in intimal hyperplasia. Astragalus–Angelica combination has a protective effect on the cardiovascular system. The inhibition effect of different Astragalus–Angelica combination on the hyperplastic intima after vascular balloon injury in rats was investigated in this study. Astragalus–Angelica combination can inhibit the intima hyperplasia after balloon injury, in which a 1:1 ratio shows excellent results. Astragalus–Angelica combination can enhance the expression of smooth muscleα-actin...

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Inhibition of Aortic Intimal Hyperplasia and Vascular Smooth Muscle Proliferation and Extracellular Matrix Protein Expressions by Astragalus-Angelica Combination

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