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Inhibition of Aortic Intimal Hyperplasia and Vascular Smooth Muscle Proliferation and Extracellular Matrix Protein Expressions by Astragalus-Angelica Combination

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成果类型:
期刊论文
作者:
Yan, Huifang;Peng, Xiwei;Xu, Hao;Zhu, Jiahuan;Deng, Changqing*邓常清
通讯作者:
Deng, Changqing(邓常清
作者机构:
[Peng, Xiwei; Xu, Hao; Yan, Huifang; Zhu, Jiahuan] Hunan Univ Chinese Med, Mol Pathol Lab, Hunan Prov Key Lab Prevent & Treatment Integrated, Changsha 410208, Hunan, Peoples R China.
[Deng, Changqing] Hunan Univ Chinese Med, Mol Pathol Lab, Changsha 410208, Hunan, Peoples R China.
通讯机构:
[Deng, Changqing] H
Hunan Univ Chinese Med, Mol Pathol Lab, Changsha 410208, Hunan, Peoples R China.
语种:
英文
期刊:
Evidence-Based Complementary and Alternative Medicine
ISSN:
1741-427X
年:
2018
卷:
2018
页码:
1508637
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81473581]
机构署名:
本校为第一且通讯机构
院系归属:
医学院
中西医结合学院
摘要:
VSMC proliferation and ECM deposition always resulted in intimal hyperplasia. Astragalus-Angelica combination has a protective effect on the cardiovascular system. The inhibition effect of different Astragalus-Angelica combination on the hyperplastic intima after vascular balloon injury in rats was investigated in this study. Astragalus-Angelica combination can inhibit the intima hyperplasia after balloon injury, in which a 1:1 ratio shows excellent results. Astragalus-Angelica combination can enhance the expression of smooth muscle α-actin (S...

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