期刊论文

An Experimental Study on the Effect of Zedoary on the Membrane Function of Hepatocytes among Rats with Immune-Injuring Induced Hepatic Fibrosis

中文

湖南中医药大学学报

1674-070X

2003

23

1

7-8+12

10.3969/j.issn.1674-070X.2003.01.004

95A1116:国家中医药局科研项目 98111:湖南省卫生计生委科研项目

本校为第一机构

目的研究莪术对免疫性肝纤维化大鼠肝细胞膜功能的影响.方法 采用牛血清白蛋白(BSA)致大鼠肝纤维化模型,观察莪术大、小剂量对其肝功能、超氧化物歧化酶(SOD)、丙二醛(MDA)及肝细胞膜腺苷三磷酸酶(ATPase)活性的改变.结果 大剂量莪术能明显降低肝细胞膜Ca2+ -ATPase活性(P

?Objective To investigate the effect of Ezhu(Zedoary) on the membrane function of hepatocytes among rats with immune injuring iduced hepatic fibrosis.Methods The model of immune injuring induced hepatic fibrosis of rats was prepared by the use of bovine serum albumin. Then,various dosages of Zedoary were fed to the animals gastrically and liver function,SOD,MDA and ATPase activity of hepatocytic membrane were determined respectively to see the differences among them.Results The larger dosage of Zedoary could obviously decrease the activity of C...