MicroRNAs (miRs) are important in hepatocellular carcinoma (HCC) progression. miR-145-5p acts as a tumor suppressor in certain malignancies, however, its role in HCC remains unclear. The present study aimed to perform a functional analysis of miR-145-5p in HCC in order to elucidate its role in the pathogenesis of HCC. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was performed to analyze tissue and cellular expression of miR-145-5p in HCC. Following miRNA mimics transfection, cell viability, apoptosis and cells migratio...