期刊论文

Lu, F.G.

中文

中国中西医结合杂志

1003-5370

2012

32

3

380-384

国家自然科学基金资助（No.30973759） 湖南省科学基金资助（No.09JJ3054）

本校为第一机构

目的 探讨知柏地黄汤对解脲支原体(ureaplasma urealyticum,UU)感染大鼠睾丸组织病理变化和超微结构的影响.方法 经膀胱接种建立大鼠睾丸组织感染解脲支原体动物模型,将45只UU感染模型动物随机分为:知柏地黄汤治疗组[中药组,2 g/( 100 g·d)]、美满霉素治疗组[西药组,10 mg/(100 g· d)]及模型组,每组15只.另选取15只大鼠作为假手术组.予动物接种10天后开始给药,假手术组及模型组灌胃等容积生理盐水,连续灌胃22天.于停药后第2天处死动物,检测睾丸重量指数,分别以光学显微镜和透射电子显微镜观察睾丸组织的病理变化与超微结构.结果 各组大鼠左、右侧睾丸重量指数、睾丸重量指数比较,差异均无统计...

OBJECTIVE: To study the effects of Zhibai Dihuang Decocion (ZDD) on the pathological changes and the ultrastructure of the testicular tissue in the ureaplasma urealyticum (UU)-infected rats. METHODS: The UU infected animal models were established by the bladder inoculation. The 45 UU infected SD rats were randomly divided into four groups, i.e., the ZDD treatment group (at the daily dose of 2 g/100 g), the Minocycline group (at the daily dose of 10 mg/100 g), the model group, 15 in each group. Besides, another 15 rats were recruited as the sham-operation group. The medication was started 10 da...