Effects of the main active components combinations of Astragalus and Panax notoginseng on energy metabolism in brain tissues after cerebral ischemia-reperfusion in mice

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成果类型：

期刊论文

作者：

Huang, Xiao-Ping（黄小平）;Ding, Huang;Wang, Bei;Qiu, Yong-Yuan;Tang, Ying-Hong;...

通讯作者：

Deng, Chang-Qing（邓常清）

作者机构：

[Huang, Xiao-Ping; Deng, Chang-Qing] Hunan Univ Chinese Med, Mol Pathol Lab, Changsha 410208, Hunan, Peoples R China.

[Huang, Xiao-Ping; Wang, Bei; Qiu, Yong-Yuan; Zeng, Rong; Deng, Chang-Qing] Key Lab Hunan Prov Prevent & Treatment Integrated, Changsha, Hunan, Peoples R China.

[Huang, Xiao-Ping; Ding, Huang; Tang, Ying-Hong; Deng, Chang-Qing] Key Lab Hunan Univ Cell Biol & Mol Tech, Changsha, Hunan, Peoples R China.

[Deng, Chang-Qing] Hunan Univ Chinese Med, Coll Med, Xueshi Rd 300,Hanpu Sci & Technol Pk, Changsha 410208, Hunan, Peoples R China.

通讯机构：

[Deng, Chang-Qing] H

Hunan Univ Chinese Med, Coll Med, Xueshi Rd 300,Hanpu Sci & Technol Pk, Changsha 410208, Hunan, Peoples R China.

语种：

英文

关键词：

AMP-activated protein kinase;Active components combinations;Astragalus and Panax notoginseng;cerebral ischemia;energy metabolism;glucose transporter 3

期刊：

Pharmacognosy Magazine

ISSN：

0973-1296

年：

2015

卷：

期：

页码：

732-739

DOI：

10.4103/0973-1296.165572

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81102557]; Doctoral Program Foundation of Higher Education of China [20104323110001]; Aid Project for Innovation Platform Open Fund of Hunan province university [11K050, 14K068]; Key Project of Administration of traditional Chinese Medicine of Hunan province [201301, 201508]; General Project of Science and Technology Department of Hunan Province [2014SK3001]; General Project of Education Bureau of Hunan Province [11C0963]; Ministry of Education Key Laboratory Open Fund Eestablished by the Province and the Ministry [ZYNK201405]

机构署名：

本校为第一且通讯机构

院系归属：

医学院

中西医结合学院

摘要：

BACKGROUND: Astragalus and Panax notoginseng are traditional Chinese medicines used for the treatments of cardio-cerebrovascular ischemic diseases, astragaloside IV (AST IV) and ginsenoside Rg1 (Rg1), ginsenoside Rb1 (Rb1), notoginsenoside R1 (R1) are their active components. OBJECTIVE: The purpose of this work was to investigate the effect of AST IV combined with Rg1, Rb1, R1 on energy metabolism in brain tissues after cerebral ischemia-reperfusion in mice. MATERIALS AND METHODS: C57BL/6 mice were randomly divided into 11 groups, treated for 3 days. At 1 h after the last administration, the m...

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Effects of the main active components combinations of Astragalus and Panax notoginseng on energy metabolism in brain tissues after cerebral ischemia-reperfusion in mice

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