Objective To study the relationship between the change of abnormal tongue fur, epidermal growth factor receptor (h-EGFR) of epithelial cells of tongue and the content change of epidermal growth factor (h-EGF) in saliva and serum of the patient with chronic hepatitis B, and explore the action of h-EGF on formation of abnormal tongue fur. Methods The subject group was 128 patients with chronic hepatitis B and the control group was 15 patients with other diseases in digestive system, 15 patients with other system diseases and 15 healthy people...