Primary open-angle glaucoma is a disease whose pathogenesis is more complex and more difficult to diagnose and treat. The incidence of occult disease in patients with early disease often shows no obvious symptoms. In late stage development, vision loss often visits, but this time whether drugs or surgery can not effectively improve vision and optic nerve has been damaged significantly and is difficult to reverse. However, current research on primary open-angle glaucoma pathogenesis is of no unified conclusion. The paper reviews the recent primary open-angle glaucoma in the pathogenesis of the ...