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Sperm-associated antigen 9 is upregulated in hepatocellular carcinoma tissue and enhances QGY cell proliferation and invasion in vitro

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成果类型:
期刊论文
作者:
Ren, Biqiong*任碧琼);Zou, Guoying;He, Junyu;Huang, Yiran;Ma, Guoan;...
通讯作者:
Ren, Biqiong(任碧琼
作者机构:
[Ren, Biqiong; Zou, Guoying; He, Junyu; Xu, Guofeng; Li, Yong] Hunan Prov Second Peoples Hosp, Dept Clin Lab, 427 Furong Rd, Changsha 410007, Hunan, Peoples R China.
[Ren, Biqiong; Zou, Guoying; He, Junyu; Huang, Yiran; Xu, Guofeng; Li, Yong] Hunan Univ Chinese Med, Clin Med Sch, Changsha 410007, Hunan, Peoples R China.
[Ren, Biqiong; Zou, Guoying; He, Junyu; Ma, Guoan; Yu, Ping] Cent S Univ, Sch Basic Med, Dept Immunol, Changsha 410078, Hunan, Peoples R China.
[Ma, Guoan] Tumor Hosp Hunan Prov, Dept Hepatobiliary Dis, Changsha 410008, Hunan, Peoples R China.
通讯机构:
[Ren, Biqiong] H
Hunan Prov Second Peoples Hosp, Dept Clin Lab, 427 Furong Rd, Changsha 410007, Hunan, Peoples R China.
语种:
英文
关键词:
cell cycle;cell migration;cell proliferation;hepatoma carcinoma;short interfering RNA;sperm-associated antigen 9
期刊:
Oncology Letters
ISSN:
1792-1074
年:
2018
卷:
15
期:
1
页码:
415-422
基金类别:
Hunan Provincial Health Department Foundation [B2011-099]; Key Project of Hunan Provincial Second People's Hospital Fund Foundation [2013-1]
机构署名:
本校为其他机构
院系归属:
临床医学院
摘要:
The incidence and mortality rates of hepatocellular carcinoma (HCC) are higher in China compared with in other countries. Further research is required in order to improve the diagnosis and treatment of HCC. Sperm-associated antigen 9 (SPAG9) protein has been revealed to serve an important function in cancer progression; however, the underlying mechanisms remain to be elucidated. The present study investigated the expression level of SPAG9 in HCC tissues using quantitative-polymerase chain reaction, immunohistochemistry and western blotting, and...

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