期刊论文

Effect of yiqihuoxuefa on expression of bFGF and GFAP in rabbit retina injured by laser photocoagulation

中文

眼科新进展

1003-5141

2011

31

3

220-222,227

10.13389/j.cnki.rao.2011.03.001

06JJ0056:湖南省自然科学基金

本校为其他机构

目的 探讨益气活血法对兔视网膜激光光凝损伤的防治作用和相应机理. 方法 50只健康有色家兔随机分为正常对照组、模型对照组、黄芪组、蛴螬组、益气活血组.黄芪组每天给予黄芪水煎液5 mL·kg-1灌胃;蛴螬组每天给予蛴螬水提液5 mL·kg-1灌胃;益气活血组每天给予益气活血水煎液5 mL·kg-1灌胃;正常对照组、模型对照组给予等量生理盐水灌胃,每天一次.于造模后第7天、第14天分两批处死实验兔,行眼球摘除术,视网膜组织固定后,石蜡包埋,作病理组织学切片,采用免疫组织化学法观察视网膜碱性成纤维细胞生长因子(basic fibroblast growth factor,bFGF)及胶质纤维酸性蛋白(glial fibrillary acidic protei...

Objective To discuss the protective effect and mechanism of yiqihuoxuefa on rabbit retina injured by laser photocoagulation.Methods Fifty chinchilla rabbits were divided randomly into normal group,model group,astragalus group,grub group and yiqihuoxuefang group.Astragalus at dose of 5 mL·kg-1 was given in astragalus group once a day;Grub at dose of 5 mL·kg-1 was given in grub group;Yiqihuoxuefang at dose of 5 mL·kg-1 was given in yiqihuoxuefang group;Same volume PBS was given in normal group and model group,once a day.At the 7th and 14th day...