作者:
Jinhong Liu;GuoZuo Xiong;DuanFang Liao;Qinhui Tuo
期刊:
African Journal of Pharmacy and Pharmacology,2013年7(19):1144-1147 ISSN:1996-0816
作者机构:
[Jinhong Liu; GuoZuo Xiong; DuanFang Liao; Qinhui Tuo] Learning Key Laboratory for Pharmacoproteomics,School of Life Science and Technology,University of South China;[Jinhong Liu; GuoZuo Xiong; DuanFang Liao; Qinhui Tuo] Department of General Surgery,The Second Affiliated Hospital in University of South China;[Jinhong Liu; GuoZuo Xiong; DuanFang Liao; Qinhui Tuo] Department of Traditional Chinese Diagnotics,School of Pharmacy,Hunan University of Chinese Medicine
会议名称:
第11届全国脂质与脂蛋白学术会议
会议时间:
2012-09-21
会议地点:
太原
会议论文集名称:
第11届全国脂质与脂蛋白学术会议论文集
摘要:
Death domain-associated protein (Daxx) was originally identiï¬ed as a protein that speciï¬cally binds to the death domain of the transmembrane death receptor Fas (also called CD95) in the cytoplasm and potentiates Fas-induced apoptosis. Over expression of Daxx enhances Fas-mediated apoptosis and activates the Jun N-terminal kinase (JNK) pathway. Daxx was found in the nuclears where it localizes to promyelocytic leukaemia (PML) oncogenic domains (PODs). As a highly conserved nuclear protein, Daxx plays an important role in proapoptosis, antiapoptosis and transcriptional regulation. This article reviews the latest advances in the study of the biological function of Daxx.
期刊:
International Journal of Cancer,2013年132(2):496-497 ISSN:0020-7136
通讯作者:
Cao, Deliang
作者机构:
[Cao, Deliang] So Illinois Univ, Sch Med, Simmons Canc Inst, Dept Med Microbiol Immunol & Cell Biol, Springfield, IL 62794 USA.;[Liao, Duan-Fang] Hunan Univ Chinese Med, Div Stem Cell Regulat & Applicat, State Key Lab Chinese Med Powder & Med Innovat Hu, Changsha, Hunan, Peoples R China.;[Cao, Deliang] So Illinois Univ, Sch Med, Simmons Canc Inst, Dept Med Microbiol Immunol & Cell Biol, 913 N Rutledge St, Springfield, IL 62794 USA.
通讯机构:
[Cao, Deliang] S;So Illinois Univ, Sch Med, Simmons Canc Inst, Dept Med Microbiol Immunol & Cell Biol, 913 N Rutledge St, Springfield, IL 62794 USA.
摘要:
The International Journal of Value-Based Management presents papers which clarify the role of values in organizational behavior and in the process of decision making. The Journal's main purpose is to keep readers abreast of developments and new techniques in all areas of management. To this end, case studies relating to specific companies, products, and industries are included, as are empirical studies, especially those adopting a comparative cultural viewpoint. Papers exploring the relationships between personal/organizational values and performance are published, as are comparative management studies offering specific ramifications for the practising manager within a particular culture. The International Journal of Value-Based Management aimes at an international readership, it provides indispensable reading for the modern manager and business professional, management scientist, business school faculty and their students at every level, and all those who seek to understand the impact that values and ethics have on the modern business.Coverage in the Journals@Ovid database begins with the Volume 10, Issue 1, 1997 issue.
作者机构:
[Shuhua Cui; Qinhui Tuo; DuanFang Liao] Learning Key Laboratory for Pharmacoproteomics,School of Life Science and Technology,University of South China;[Shuhua Cui; Qinhui Tuo; DuanFang Liao] Department of Traditional Chinese Diagnotics,School of Pharmacy,Hunan University of Chinese Medicine
会议名称:
第11届全国脂质与脂蛋白学术会议
会议时间:
2012-09-21
会议地点:
太原
会议论文集名称:
第11届全国脂质与脂蛋白学术会议论文集
摘要:
<正>Objective:The aim of the present study was to determine the effect of Daxx on apoptosis of RAW264.7 cells induced by Chol.MpCD. Methods:The eukaryotic vector of Daxx was constructed to be stably tr
作者机构:
[Tang, Zhenwang] S China Univ, Affiliated Hosp 1, Dept Cardiol, Hengyang 421001, Peoples R China.;[Li, Xingsheng] Chongqing Med Univ, Affiliated Hosp 2, Dept Geriatr Cardiol, Chongqing 400010, Peoples R China.;[Liao, Duanfang] Hunan Univ Chinese Med, Dept Pharmacol, Changsha 410007, Hunan, Peoples R China.
通讯机构:
[Tang, Zhenwang] S;S China Univ, Affiliated Hosp 1, Dept Cardiol, Hengyang 421001, Peoples R China.
关键词:
The beta 2-adrenergic receptor gene;Polymorphism;Hypertension;Meta-analysis
摘要:
The beta 2-adrenergic receptor (beta 2-AR) gene has been implicated in the pathogenesis of hypertension. However, the results have been conflicting. In this study, we performed a meta-analysis to assess the associations of 46A/G and 79C/G polymorphisms in beta 2-AR gene with hypertension risk in Han Chinese population. Published literature from PubMed, ISI Web of Science, Embase databases, CNKI, CBM and Wanfang Data were retrieved. Pooled odds ratio (OR) with 95 % confidence interval (CI) was calculated using fixed- or random-effects model. Eleven studies (2,058 cases and 1,459 controls) for 46A/G polymorphism and eight studies (2,219 cases and 1,495 controls) for 79C/G polymorphism were identified. The results suggested that 46A/G polymorphism G allele might increase the risk of hypertension (GG vs. AA: OR = 1.47, 95 % CI 1.20-1.82). However, no significant association was observed for 79C/G polymorphism (GG vs. CC: OR = 1.05, 95 % CI 0.61-1.79). The results indicated that 46A/G polymorphism in the beta 2-AR gene was associated with hypertension susceptibility in Han Chinese population.
作者机构:
Division of Stem Cell Regulation and Application, State Key Laboratory of Chinese Medicine Powder and Medicine Innovation in Hunan (incubation), Hunan University of Chinese Medicine, Changsha;Institute of Pharmacy & Pharmacology, University of South China, Hengyang Hunan, China